COLLAGEN, GLYCATION, OXIDATIVE
STRESS
AND AGEING
Dernière mise à jour / Last release : March 7, 2008.
Themes / Main topics
Biochimie du collagene / Biochemistry of collagen
Glycation et vieillissement / Glycation and ageing
Stress oxydatif et biologie cellulaire / Oxidative stress and cell biology
Edito
Fatty sugars
Carbohydrates are classified through high-glycemic-index and low-glycemic-index by reference to their intestinal absorption. Carbohydrates with a high-glycemic-index, like glucose itself, honey or starch (potatoes, white bread, white rice, corn flakes) are able to release glucose in blood faster and to increase faster the post-prandial hyperglycemic level than sugars with a low-glycemic index. Fast absorption sugars are taken into account in the case of diabetes but their relationship with overweight is confuse. In non diabetic peoples, they are considered to be useful during physical exercise. But, by the insulin secretion increase, carbohydrates with a high-glycemic-index stimulate lipid synthesis into adipocytes and fat deposit. Considering the importance of overweight prevalence and to focus the attention on the relationship between fast absorption sugars and the fat, we suggest to name them : fatty sugars.
Publications
Frey J. Collagen, ageing and nutrition. Clin Chem Lab Med. 2004 Jan;42(1):9-12.
Meli
M, Perier C, Ferron C, Parssegny F, Denis C, Gonthier R, Laurent B, Reynaud
E, Frey J, Chamson A. Serum pentosidine as an indicator of Alzheimer's
disease. J. Alzheimer Dis. 2002 ; 4 : 93-96.
Frey
J. Bovine spongiform encephalopathy: are the cows mad or full of carbohydrates?
Clin Chem Lab Med 2002 Feb;40(2):101-3
Massoubre C, Rattner A, Pellet J, Frey J, Chamson A. La cholécystokinine
: mise au point. Nutr. Clin. Metabol. 2002 ; 16 : 4-13.
Chepda
T, Cadau M, Lassabliere F, Reynaud E, Perier C, Frey J, Chamson A. Synergy
between ascorbate and alpha-tocopherol on fibroblasts in culture. Life
Sci 2001 Aug 24;69(14):1587-96.
Raby N, Frey J, Miadi H, Fournel C, Bonneau C, Le J, Chamson A, Perier C. Acomparison of diferent methodologies for estimating LDL-cholesterol. Medical Biochem. 2001;1:307-313.
Massoubre C, Rattner A, Lang F, Frey J, Périer C. Cholecystikinin characterization in urine by HPLC and immunoblotting. J. Liquid. Chrom. Rel. Technol. 2001;24:1365-1369.
Frey J. Is there sugar in the Alzheimer's disease? Ann Biol Clin (Paris). 2001 May;59(3):253-7.